AnalyzeDirect Eilaghi A, Kassner A, Sitartchouk I, Francis PL, Jakubovic R, Feinstein A, Aviv RI. Normal-appearing white matter permeability distinguishes poor cognitive performance in processing speed and working memory. AJNR Am J Neuroradiol. November 2013;34(11):2119-2124.
Full Text – Open Access
Publication Date
November 2013
How Analyze was Used
“Segmented regions were imported into Analyze 8.0 (Analyze AVW…), and WM lesion regions of interest were manually drawn. Brain parenchymal and WM lesion fractions were calculated as previously described [Aviv et al. 2012]. NAWM regions of interest were selected from within the WM tissue by use of four 16-voxel blocks located in anterior and posterior regions of both hemispheres.”
Keywords
Cognition
Cognition Disorders/etiology/pathology/physiopathology
Diagnosis, Differential
Diffusion Tensor Imaging/methods
Female
Humans
Male
Memory, Short-Term
Middle Aged
Multiple Sclerosis, Chronic Progressive/complications/pathology/physiopathology
Nerve Fibers, Myelinated/pathology
Reference Values
Reproducibility of Results
Sensitivity and Specificity
Author Affiliation(s)
Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. (AE, PLF, RJ, RIA)
Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. (AE)
Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada. (AE)
Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada. (AK, IS, RIA)
Department of Physiology and Experimental Medicine, Hospital for Sick Children, Toronto, Ontario, Canada. (AK)
ID# 939
Tags: Chronic Progressive Multiple Sclerosis/complications/pathology/physiopathology, Cognition, Cognition Disorders/etiology/pathology/physiopathology, Differential Diagnosis, Diffusion Tensor Imaging/methods, Female, Humans, Male, Middle Aged, Myelinated Nerve Fibers/pathology, Reference Values, Reproducibility of Results, Sensitivity and Specificity, Short-Term Memory