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Bouilleret V, Hogan RE, Velakoulis D, Salzberg MR, Wang L, Egan GF, O’Brien TJ, Jones NC. Morphometric abnormalities and hyperanxiety in genetically epileptic rats: a model of psychiatric comorbidity? Neuroimage. April 2009;45(2):267-274.

Publication Date
April 2009

How Analyze was Used
“Quantification of the volume of selected brain regions was performed using Analyze 8.1 … in which Regions- Of-Interest (ROI) were manually drawn on consecutive axial MRI slices by an investigator blinded to the strain of animal.”

Keywords
Animals
Anxiety/complications/pathology
Brain/pathology
Epilepsy/complications/pathology
Female
Genetic Predisposition to Disease/genetics
Imaging, Three-Dimensional/methods
Magnetic Resonance Imaging (MRI)/methods
Rats
Reproducibility of Results
Sensitivity and Specificity

Author Affiliation(s)
Department of Medicine — Royal Melbourne Hospital, University of Melbourne, Royal Parade, Parkville, Victoria 3052, Australia. (VB, TJO, NCJ)

Department of Neurophysiology and Epilepsy, ApHp, CHU Bicetre, Paris 94275, France. (VB)

Department of Neurology, Washington University, St. Louis, MO 63130, US. (REH)

Melbourne Neuropsychiatry Centre, Royal Melbourne Hospital, University of Melbourne, Victoria 3052, Australia. (DV)

Department of Psychiatry, St. Vincent’s Health, The University of Melbourne, Victoria 3052, Australia. (MRS)

Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, US. (LW)

Howard Florey Institute, Parkville, Victoria 3050, Australia. (GFE)

Department of Neurology (RMH), University of Melbourne, Victoria 3052, Australia. (TJO)

ID# 1234

Tags: Animals, Anxiety/complications/pathology, Brain/pathology, Epilepsy/complications/pathology, Female, Genetic Predisposition to Disease/genetics, Magnetic Resonance Imaging (MRI)/methods, Rats, Reproducibility of Results, Sensitivity and Specificity, Three-Dimensional Imaging/methods