AnalyzeDirect Lin J, Zhu X, Chade AR, Jordan KL, Lavi R, Daghini E, Gibson ME, Guglielmotti A, Lerman A, Lerman LO. Monocyte chemoattractant proteins mediate myocardial microvascular dysfunction in swine renovascular hypertension. Arterioscler Thromb Vasc Biol. November 2009;29(11):1810-1816.
Full Text – Open Access
Publication Date
November 2009
How Analyze was Used
“Pigs were scanned by either electron beam (C-150, Imatron) or 64-slice multidetector (Somatom Sensation-64, Siemens) fast CT, which provide very similar assessments of MP and FVV,7 and images analyzed with ANALYZE (… see supplemental materials).”
Keywords
Analysis of Variance
Animals
Capillary Permeability/physiology
Cells, Cultured
Collagenases/metabolism
Collateral Circulation/physiology
Coronary Circulation/physiology
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme-Linked Immunosorbent Assay
Female
Hypertension, Renovascular/drug therapy/metabolism
Hypertrophy, Left Ventricular/drug therapy/metabolism/physiopathology
Immunohistochemistry
Matrix Metalloproteinase 13/metabolism
Microcirculation/drug effects/physiology
Monocyte Chemoattractant Proteins/metabolism/pharmacology
Myocardium/metabolism
Neovascularization, Physiologic
Probability
Random Allocation
Sus scrofa
Swine
Tissue Inhibitor of Metalloproteinase-1/metabolism
Author Affiliation(s)
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, US. (JL, XZ, ARC, KLJ, RL, ED, MEG, LOL)
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, US. (AL, LOL)
Angelini Research Center, ACRAF, S. Palomba-Pomezia, Rome, Italy. (AG)
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, US. (ARC)
Department of Anesthesia and Perioperative Medicine, London Health Care Science Center, University of Western Ontario, Canada. ( RL)
ID# 1287
Tags: Analysis of Variance, Animal Disease Models, Animals, Capillary Permeability/physiology, Collagenases/metabolism, Collateral Circulation/physiology, Coronary Circulation/physiology, Cultured Cells, Drug Dose-Response Relationship, Enzyme-Linked Immunosorbent Assay, Female, Immunohistochemistry, Left Ventricular Hypertrophy/drug therapy/metabolism/physiopathology, Matrix Metalloproteinase 13/metabolism, Microcirculation/drug effects/physiology, Monocyte Chemoattractant Proteins/metabolism/pharmacology, Myocardium/metabolism, Physiologic Neovascularization, Probability, Random Allocation, Renovascular Hypertension/drug therapy/metabolism, Sus scrofa, Swine, Tissue Inhibitor of Metalloproteinase-1/metabolism