AnalyzeDirect Dennis MS, Jin H, Dugger D, Yang R, McFarland L, Ogasawara A, Williams S, Cole MJ, Ross S, Schwall R. Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent. Cancer Res. January 2007;67(1):254-261.
Full Text – Open Access
Publication Date
January 2007
How Analyze was Used
“Images were coregistered by geometric transformation and fused with Analyze (AnalyzeDirect, Inc., Lenexa, KS) and then rendered to make the composite images (Amira).”
Keywords
Albumins/chemistry/diagnostic use/pharmacokinetics
Amino Acid Sequence
Animals
Antibodies, Monoclonal/chemistry/pharmacokinetics
Antibodies, Monoclonal, Humanized
Female
Humans
Image Processing, Computer-Assisted
Immunoconjugates/chemistry/diagnostic use/pharmacokinetics
Immunoglobulin Fragments/chemistry/diagnostic use/metabolism
Mammary Neoplasms, Experimental/metabolism/radionuclide imaging
Mice
Mice, Inbred BALB C
Mice, Transgenic
Molecular Sequence Data
Receptor, ErbB-2/biosynthesis/metabolism
Author Affiliation(s)
Departments of 1Antibody Engineering, Genentech, Inc., South San Francisco, CA, US. (MSD)
Translational Oncology, Genentech, Inc., South San Francisco, CA, US. (HJ, DD, RY, SR, RS)
Biomedical Imaging, Genentech, Inc., South San Francisco, CA, US. (LM, AO, SW, MJC)
ID# 1792
Tags: Albumins/chemistry/diagnostic use/pharmacokinetics, Amino Acid Sequence, Animals, Computer-Assisted Image Processing, ErbB-2 Receptor/biosynthesis/metabolism, Experimental Mammary Neoplasms/metabolism/radionuclide imaging, Female, Humanized Monoclonal Antibodies, Humans, Immunoconjugates/chemistry/diagnostic use/pharmacokinetics, Immunoglobulin Fragments/chemistry/diagnostic use/metabolism, Inbred BALB C Mice, Mice, Molecular Sequence Data, Monoclonal Antibodies/chemistry/pharmacokinetics, Transgenic Mice