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Jensen JE, Miller J, Williamson PC, Neufeld RWJ, Menon RS, Malla A, Manchanda R, Schaefer B, Densmore M, Drost DJ. Focal changes in brain energy and phospholipid metabolism in first-episode schizophrenia: 31P-MRS chemical shift imaging study at 4 Tesla. Br J Psychiatry. May 2004;184:409-415.

Full Text – Open Access

Publication Date
May 2004

How Analyze was Used
“Extraneous tissue with signal intensities similar to neural tissue or cerebrospinal fluid, such as skin and subcutaneous lipid, was removed from the segmented images using commercial software (Analyze 4.0 for PC …) to avoid it being counted as neuronal tissue in the final volumetric analysis.”

Keywords
Adult
Analysis of Variance
Brain/metabolism
Energy Metabolism
Female
Gyrus Cinguli/metabolism
Humans
Magnetic Resonance Spectroscopy/methods
Male
Phospholipids/metabolism
Schizophrenia/metabolism

Author Affiliation(s)
Brain Imaging Center, McLean Hospital, Belmont, MA, US. (JEJ)

Department of Psychiatry, Harvard Medical School, Boston, MA, US. (JEJ)

Department of Medical Biophysics, University of Western Ontario, London, Ontario. (JM, PCW, RSM, DJD)

Diagnostic Radiology and Nuclear Medicine, St Joseph’s Health Care, London, Ontario. (JM, MD, DJD)

Department of Psychiatry, University of Western Ontario, London, Ontario. (PCW, DJD)

Department of Psychology, University of Western Ontario, London, Ontario. (RWJN)

Laboratory for Magnetic Resonance Imaging Research, Robarts Research Institute, London, Ontario. (RSM)

Douglas Hospital, McGill University, Montreal, Quebec. (AM)

Department of Psychiatry, University of Western Ontario. (RM, BS)

ID# 2241

Tags: Adult, Analysis of Variance, Brain/metabolism, Energy Metabolism, Female, Gyrus Cinguli/metabolism, Humans, Magnetic Resonance Spectroscopy/methods, Male, Phospholipids/metabolism, Schizophrenia/metabolism