AnalyzeDirect Coggan JS, Bartol TM, Esquenazi E, Stiles JR, Lamont S, Martone ME, Berg DK, Ellisman MH, Sejnowski TJ. Evidence for ectopic neurotransmission at a neuronal synapse. Science. July 2005;309(5733):446-451.
Full Text – Open Access
Publication Date
July 2005
How Analyze was Used
“Cross-sectional view about halfway through the middle of an E15 chick CG [ciliary ganglion] acquired with serial EM tomography and visualization software AnalyzeAVW.”
Keywords
Acetylcholine/metabolism
Acetylcholinesterase/metabolism
Algorithms
Animals
Chick Embryo
Computer Simulation
Diffusion
Excitatory Postsynaptic Potentials
Ganglia, Parasympathetic/physiology/ultrastructure
Image Processing, Computer-Assisted
Mathematics
Microscopy, Electron
Models, Neurological
Monte Carlo Method
Patch-Clamp Techniques
Probability
Receptors, Nicotinic/metabolism
Sensitivity and Specificity
Synapses/physiology/ultrastructure
Synaptic Membranes/metabolism
Synaptic Transmission
Synaptic Vesicles/metabolism
Author Affiliation(s)
Computational Neurobiology Laboratory, The Salk Institute, La Jolla, CA 92037, US. (JSC, TMB, TJS)
Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, MD, 20815, US. (TJS)
National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, US. (JSC, EE, SL, MEM, MHE)
Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, CA 92093, US. (MEM, MHE)
Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, US. (EE, DKB, TJS)
Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA 15213, US. (JRS)
Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, US. (JRS)
Center for Theoretical Biological Physics, University of California, San Diego, La Jolla, CA, 92093–0374, US. (TMB, TJS)
ID# 2151
Tags: Acetylcholine/metabolism, Acetylcholinesterase/metabolism, Algorithms, Animals, Chick Embryo, Computer Simulation, Computer-Assisted Image Processing, Diffusion, Electron Microscopy, Excitatory Postsynaptic Potentials, Mathematics, Monte Carlo Method, Neurological Models, Nicotinic Receptors/metabolism, Parasympathetic Ganglia/physiology/ultrastructure, Patch-Clamp Techniques Probability, Sensitivity and Specificity, Synapses/physiology/ultrastructure, Synaptic Membranes/metabolism, Synaptic Transmission, Synaptic Vesicles/metabolism