AnalyzeDirect Leyton J, Latigo JR, Perumal M, Dhaliwal H, He Q, Aboagye EO. Early detection of tumor response to chemotherapy by 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo. Cancer Res. May 2005;65(10):4202-4210.
Full Text – Open Access
Publication Date
May 2005
How Analyze was Used
“The image data sets obtained were transferred to a SUN workstation … and visualized using the Analyze software (version 6.0).”
Keywords
Adenosine Triphosphate/metabolism
Animals
Antineoplastic Agents/pharmacology
Cell Cycle/drug effects
Cisplatin/pharmacology
Dideoxynucleosides/diagnostic use/pharmacokinetics
Fibrosarcoma/drug therapy/enzymology/etiology/radionuclide imaging
Fluorine Radioisotopes/diagnostic use
Hexokinase/metabolism
Male
Mice
Mice, Inbred C3H
Neoplasms, Radiation-Induced/drug therapy/enzymology/radionuclide imaging
Positron-Emission Tomography (PET)/methods
Radiopharmaceuticals/diagnostic use/pharmacokinetics
Thymidine Kinase/metabolism
Author Affiliation(s)
Molecular Therapy Group, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK. (JL, JRL, MP, HD, EOA)
Department of Oncology, Clinical Research Laboratory, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden. (QH)
ID# 2075
Tags: Adenosine Triphosphate/metabolism, Animals, Antineoplastic Agents/pharmacology, Cell Cycle/drug effects, Cisplatin/pharmacology, Dideoxynucleosides/diagnostic use/pharmacokinetics, Fibrosarcoma/drug therapy/enzymology/etiology/radionuclide imaging, Fluorine Radioisotopes/diagnostic use, Hexokinase/metabolism, Inbred C3H Mice, Male, Mice, Positron-Emission Tomography (PET)/methods, Radiation-Induced Neoplasms/drug therapy/enzymology/radionuclide imaging, Radiopharmaceuticals/diagnostic use/pharmacokinetics, Thymidine Kinase/metabolism