Analyze Publications Database

Deficits in spatial learning and memory is associated with hippocampal volume loss in aged apolipoprotein E4 mice

Yin JX, Turner GH, Lin HJ, Coons SW, Shi J. Deficits in spatial learning and memory is associated with hippocampal volume loss in aged apolipoprotein E4 mice. J Alzheimers Dis. July 2011;27(1):89-98.

Publication Date
July 2011

How Analyze was Used
“To calculate volume, regions of interest (ROI) were manually traced for the whole brain, cortex, hippocampus, ventricle, caudate putamen, and corpus callosum by using the image processing software Analyze 7.0 package (AnalyzeDirect, Inc. Overland Park, KS).”

Keywords
Age Factors
Aging/pathology
Analysis of Variance
Animals
Apolipoprotein E4/deficiency/genetics
Hippocampus/pathology
Humans
Learning Disorders/genetics/pathology
Magnetic Resonance Imaging (MRI)
Maze Learning
Memory/physiology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Space Perception

Author Affiliation(s)
Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, US. (JxY, HjL JS)

Keller Center for Imaging Innovation, Barrow Neurological Institute, Phoenix, AZ, US. (GHT)

Department of Pathology, Barrow Neurological Institute, Phoenix, AZ, US. (SWC)

ID# 655

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