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Hu T, Bao W, Lenhard S, Schaeffer T, Yue T, Jucker B, Willette R. Captopril blunts cardiac remodeling, prevents dysfunction, and improves survival in two different murine models of heart failure. Paper presented at: International Society for Magnetic Resonance in Medicine Twelfth Scientific Meeting and Exhibition; May 2004; Kyoto, Japan.

Publication Date
May 2004

How Analyze was Used
“Image analysis was performed using ANALYZE software package (AnalyzeDirect, KS), the ROI tools were used to select the areas of interest (septum and left ventricular free wall). Left-ventricular functional data was also analyzed providing left- ventricular end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), stroke volume (SV), cardiac output (CO), and LV mass data.”

Keywords
Captopril
Cardiac Gated Imaging Techniques
Disease Models, Animal
Disease Progression
Heart Failure
Magnetic Resonance Imaging (MRI)
Mice
Myocardial Infarction
Ventricular Function
Ventricular Remodeling

Author Affiliation(s)
CVU-CEDD, GlaxoSmithKline, King of Prussia, PA, US.

ID# 2347

Tags: Animal Disease Models, Captopril, Cardiac Gated Imaging Techniques, Disease Progression, Heart Failure, Magnetic Resonance Imaging (MRI), Mice, Myocardial Infarction, Ventricular Function, Ventricular Remodeling