Hampel H, Teipel SJ, Bayer W, Alexander GE, Schwarz R, Schapiro MB, Rapoport SI, Möller HJ. Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer’s disease. J Neurol Sci. February 2002;194(1):15-19.
Publication Date
February 2002
How Analyze was Used
“The volumes of the right and left hippocampus–amygdala formation (HAF) were measured by one investigator (WB) blinded to clinical data of the subjects using the sagittally oriented T1-weighted volumetric MRI sequence and ANALYZETM software … on an SGI … workstation.”
Keywords
Age Factors
Aged
Aging
Alzheimer Disease/diagnosis/pathology
Amygdala/pathology
Biopsy
Discriminant Analysis
Female
Hippocampus/pathology
Humans
Image Processing, Computer-Assisted/methods
Magnetic Resonance Imaging (MRI)
Male
Predictive Value of Tests
ROC Curve
Sensitivity and Specificity
Author Affiliation(s)
Dementia Research and Neuroimaging Section, Memory Clinic, Department of Psychiatry, Ludwig-Maximilian University, Nussbaumstr.7, 80336 Munich, Germany. (HH, SJT, WB, RS, HJM)
Arizona Alzheimer’s Research Center and Department of Psychology, Arizona State University, Tempe, AZ, US. (GEA)
Department of Pediatric Neurology, Children Hospital Medical Center, Cincinatti, OH, US. (MBS)
Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, US. (SIR)
ID# 2509
Tags: Age Factors, Aged, Aging, Alzheimer Disease/diagnosis/pathology, Amygdala/pathology, Biopsy, Computer-Assisted Image Processing/methods, Discriminant Analysis, Female, Hippocampus/pathology, Humans, Magnetic Resonance Imaging (MRI), Male, Predictive Value of Tests, ROC Curve, Sensitivity and Specificity