AnalyzeDirect Johnson HL, Chen Y, Suidan GL, McDole JR, Lohrey AK, Hanson LM, Jin F, Pirko I, Johnson AJ. A hematopoietic contribution to microhemorrhage formation during antiviral CD8 T cell-initiated blood-brain barrier disruption. J Neuroinflammation. March 2012;9:60.
Full Text – Open Access
Publication Date
March 2012
How Analyze was Used
“A blinded technician using Analyze captured axial slices from each animal. Axial slices representing z = 0 according to stereotactic coordinate criteria put forward by Kovacevic et al. were obtained using Analyze.”
Keywords
Animals
Astrocytes/drug effects
Blood-Brain Barrier
Bone Marrow Transplantation/methods
CD8-Positive T-Lymphocytes/drug effects/physiology
Capillary Permeability/drug effects
Capsid Proteins/adverse effects
Cardiovirus Infections/complications
Disease Models, Animal
Flow Cytometry
Fluorescein-5-isothiocyanate/metabolism
Glial Fibrillary Acidic Protein/metabolism
Hematinics
Intracranial Hemorrhages/etiology/surgery/virology
Magnetic Resonance Imaging (MRI)
Mice
Mice, Inbred Strains
Motor Activity/physiology
Rotarod Performance Test
Theilovirus/pathogenicity
Viral Proteins/adverse effects
Author Affiliation(s)
Departments of Neurology, Mayo Clinic, Rochester, MN, US. (HLJ, IP, AJJ)
Departments of Immunology, Mayo Clinic, Rochester, MN, US. (HLJ, LMH, FJ, AJJ)
Departments of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH, US. (YC, AKL)
Departments of Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, US. (GLS, JRM, AJJ)
Departments of Immunology and Neurology, Mayo Clinic, Rochester, MN 55902, US. (AJJ)
ID# 567
Tags: Animal Disease Models, Animals, Astrocytes/drug effects, Blood-Brain Barrier, Bone Marrow Transplantation/methods, Capillary Permeability/drug effects, Capsid Proteins/adverse effects, Cardiovirus Infections/complications, CD8-Positive T-Lymphocytes/drug effects/physiology, Flow Cytometry, Fluorescein-5-isothiocyanate/metabolism, Glial Fibrillary Acidic Protein/metabolism, Hematinics, Inbred Strains Mice, Intracranial Hemorrhages/etiology/surgery/virology, Magnetic Resonance Imaging (MRI), Mice, Motor Activity/physiology, Rotarod Performance Test, Theilovirus/pathogenicity, Viral Proteins/adverse effects