AnalyzeDirect Renner DN, Jin F, Litterman AJ, Balgeman AJ, Hanson LM, Gamez JD, Chae M, Carlson BL, Sarkaria JN, Parney IF, Ohlfest JR, Pirko I, Pavelko KD, Johnson AJ. Effective treatment of established GL261 murine gliomas through picornavirus vaccination-enhanced tumor antigen-specific CD8+ T cell responses. PLoS One. May 2015;10(5):e0125565.
Full Text – Open Access
Publication Date
May 2015
How Analyze was Used
“Analysis of tumor size was achieved using Analyze 11.0 software (Fig 1A), which allows for volumetric measurements of 3D renderings of the gliomas.”
Keywords
Brain
CD8-Positive T-Lymphocytes
Disease Models, Animal
Glioblastoma
Glioma
Immune System
Immunization
Magnetic Resonance Imaging (MRI)
Mice
Perforin
Picornaviridae
T-Lymphocytes, Cytotoxic
Treatment Outcome
Vaccination
Author Affiliation(s)
Neurobiology of Disease Graduate Program, Mayo Clinic, Rochester, MN, US. (DNR)
Department of Immunology, Mayo Clinic, Rochester, MN, US. (DNR, FJ, LMH, IFP, KDP, AJJ)
Department of Neurosurgery, University of Minnesota, Minneapolis MN, US. (AJL, JRO)
Summer Undergraduate Research Fellowship, Mayo Clinic, Rochester, MN, US. (AJB)
Department of Neurology, Mayo Clinic, Rochester, MN, US. (JDG, IP, AJJ)
Department of Neurosurgery, Mayo Clinic, Rochester, MN, US. (MC, IFP)
Department of Radiation Oncology, Mayo Clinic, Rochester, MN, US. (BLC, JNS)
ID# 2458
Tags: Animal Disease Models, Brain, Cd8-Positive T-Lymphocytes, Cytotoxic T-Lymphocytes, Glioblastoma, Glioma, Immune System, Immunization, Magnetic Resonance Imaging (MRI), Mice, Perforin, Picornaviridae, Treatment Outcome, Vaccination