AnalyzeDirect Mödder UIL, Sanyal A, Kearns AE, Sibonga JD, Nishihara E, Xu J, O’Malley BW, Ritman EL, Riggs BL, Spelsberg TC, Khosla S. Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology. February 2004;145(2):913-921.
Full Text – Open Access
Publication Date
February 2004
How Analyze was Used
“The raw data were reconstructed, and the resulting three-dimensional images were displayed using an image analysis software (Analyze 4.0).”
Keywords
Absorptiometry, Photon
Animals
Bone Density
Bone and Bones/chemistry
Estradiol/administration & dosage
Estrogen Receptor alpha
Estrogen Receptor beta
Estrogen Replacement Therapy
Female
Gene Expression
Histone Acetyltransferases
Mice
Mice, Inbred C57BL
Mice, Knockout
Nuclear Receptor Coactivator 1
Nuclear Receptor Coactivator 2
Organ Size/drug effects
Osteoporosis/etiology/prevention & control
Ovariectomy
RNA, Messenger/analysis
Receptors, Estrogen/genetics
Tomography, X-Ray Computed
Transcription Factors/ deficiency/genetics/physiology
Uterus/anatomy & histology
Author Affiliation(s)
Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (UILM, AS, AEK, BLR, SK)
Department of Orthopedics, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (JDS)
Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (TCS)
Physiological Imaging Research Laboratory, Department of Physiology and Biophysics, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (ELS)
Department of Molecular and Cellular Biology , Baylor College of Medicine, Houston, TX 77030, US. (EN, JX, BWOM)
ID# 2196
Tags: Animals, Bone and Bones/chemistry, Bone Density, Estradiol/administration & dosage, Estrogen Receptor alpha, Estrogen Receptor beta, Estrogen Receptors/genetics, Estrogen Replacement Therapy, Female, Gene Expression, Histone Acetyltransferases, Inbred C57BL Mice, Knockout Mice, Messenger, Mice, Nuclear Receptor Coactivator 1, Nuclear Receptor Coactivator 2, Organ Size/drug effects, Osteoporosis/etiology/prevention & control, Ovariectomy, Photon Absorptiometry, RNA/analysis, Transcription Factors/ deficiency/genetics/physiology, Uterus/anatomy & histology, X-Ray Computed Tomography