Analyze Publications Database

Differential tumor-targeting abilities of three single-domain antibody formats

Bell A, Wang ZJ, Arbabi-Ghahroudi M, Chang TA, Durocher Y, Trojahn U, Baardsnes J, Jaramillo ML, Li S, Baral TN, O’Connor-McCourt M, Mackenzie R, Zhang J. Differential tumor-targeting abilities of three single-domain antibody formats. Cancer Lett. March 2010;289(1):81-90.

Publication Date
March 2010

How Analyze was Used
“The calculated concentrations of radioactivity were multiplied by the volume of each region of interest [Sakaue et al. 2003] to determine total radioactivity present within regions. ROI was analyzed using Analyze AVW 3.0 software.”

Keywords
Amino Acid Sequence
Animals
Camelids, New World
Cell Line, Tumor
Drug Delivery Systems
Female
Humans
Immunoglobulin Fragments/administration & dosage/genetics/pharmacology
Male
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Pancreatic Neoplasms/drug therapy
Protein Engineering
Receptor, Epidermal Growth Factor/drug effects/genetics
Sequence Alignment

Author Affiliation(s)
Institute for Biological Sciences, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, Canada K1A 0R6. (AB, MAG, SL, TNB, RM, JZ)

Department of Radiology, The University of Texas HSC at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, US. (ZJW, TAC)

Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, QC, Canada. (YD, UT, JB, MLJ, MOM)

ID# 1144

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