AnalyzeDirect Mannheim D, Herrmann J, Bonetti PO, Lavi R, Lerman LO, Lerman A. Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. Atherosclerosis. June 2011;216(2):283-291.
Full Text – Open Access
Publication Date
June 2011
How Analyze was Used
“The images were reconstructed and analyzed using Analyze® software package… [Bonetti et al. 2002, Rodgriguez-Porcel et al. 2000].”
Keywords
Animals
Diastole/drug effects
Disease Models, Animal
Female
Heart Failure/blood
Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
Hydroxyproline/blood
Hypercholesterolemia/drug therapy
Lipids/chemistry
Microcirculation
Microvessels
Myocardium/pathology
Simvastatin/therapeutic use
Swine
Tomography, X-Ray Computed/methods
X-Ray Microtomography/methods
Author Affiliation(s)
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, US. (DM, JH, LOL, AL)
Division of Cardiology, Kantonsspital Graubuenden, Chur, Switzerland. (POB)
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, US. (RL, LOL)
ID# 773
Tags: Animal Disease Models, Animals, Diastole/drug effects, Female, Heart Failure/blood, Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use, Hydroxyproline/blood, Hypercholesterolemia/drug therapy, Lipids/chemistry, Microcirculation, Microvessels, Myocardium/pathology, Simvastatin/therapeutic use, Swine, X-Ray Computed Tomography/methods, X-Ray Microtomography/methods