AnalyzeDirect Stubbe T, Ebner F, Richter D, Engel O, Klehmet J, Royl G, Meisel A, Nitsch R, Meisel C, Brandt C. Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J Cereb Blood Flow Metab. January 2013;33(1):37-47.
Full Text – Open Access
Publication Date
January 2013
How Analyze was Used
“The delineable hyperintense lesion volume was determined on 20 consecutive coronal slices with 500 μm thickness using Analyze 5.0 (AnalyzeDirect, Overland Park, KS, USA) and the lesion volume was edema-corrected.”
Keywords
Animals
Antigen-Presenting Cells/immunology
CD4-Positive T-Lymphocytes/immunology
Cell Proliferation
Flow Cytometry
Forkhead Transcription Factors/genetics/immunology
Genes, Reporter
Homeodomain Proteins/genetics/immunology
Immunohistochemistry
Infarction, Middle Cerebral Artery/immunology/pathology
Interleukin-2 Receptor alpha Subunit/immunology
Lymphocyte Activation/immunology
Lymphocyte Count
Mice
Mice, Inbred C57BL
Mice, Transgenic
T-Lymphocytes, Regulatory/immunology
Time Factors
Author Affiliation(s)
Center for Anatomy, Institute of Cell Biology and Neurobiology, Charité—Universitätsmedizin Berlin, Berlin, Germany. (TS, FE, DR)
Department of Experimental Neurology, Charité—Universitätsmedizin Berlin, Berlin, Germany. (ORE, JK, GR, AM)
Institute for Microanatomy and Neurobiology, University Medicine Mainz, Johannes Gutenberg University Mainz, Mainz, Germany. (RN)
Institute of Medical Immunology, Charité—Universitätsmedizin Berlin, Berlin, Germany. (CM, CB)
ID# 498
Tags: Animals, Antigen-Presenting Cells/immunology, CD4-Positive T-Lymphocytes/immunology, Cell Proliferation, Flow Cytometry, Forkhead Transcription Factors/genetics/immunology, Homeodomain Proteins/genetics/immunology, Immunohistochemistry, Inbred C57BL Mice, Interleukin-2 Receptor alpha Subunit/immunology, Lymphocyte Activation/immunology, Lymphocyte Count, Mice, Middle Cerebral Artery Infarction/immunology/pathology, Regulatory T-Lymphocytes/immunology, Reporter Genes, Time Factors, Transgenic Mice