AnalyzeDirect Street J, Bao M, deGuzman L, Bunting S, Peale FV, Jr., Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, van Bruggen N, Redmond HP, Carano RAD, Filvaroff EH. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A. July 2002;99(15):9656-9661.
Full Text – Open Access
Publication Date
July 2002
How Analyze was Used
“VOIcallus for rabbit bones was determined with an in-house segmentation algorithm developed with ANALYZE software (AnalyzeDirect, Lenexa, KS).”
Keywords
Animals
Bone and Bones/blood supply/injuries/metabolism
Cells, Cultured
Endothelial Growth Factors/pharmacology
Femoral Fractures/physiopathology
Fracture Healing/drug effects
Humans
Lymphokines/pharmacology
Male
Mice
Mice, Inbred C57BL
Neovascularization, Physiologic/drug effects
Osteoblasts/drug effects/physiology
Rabbits
Radius/injuries
Tibia/injuries/radiography
Tomography, X-Ray Computed
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factors
Author Affiliation(s)
Department of Molecular Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, US. (MB, NF, EHF)
Department of Physiology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, US. (LdG, SB, HS, JH, NvB, RADC)
Department of Research Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, US. (FVP)
Pharmaceutical Research & Development, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, US. (JLC, AD)
Department of Academic Surgery, National University of Ireland, University College Cork, Cork, Ireland. (JS, HPR)
ID# 2508
Tags: Animals, Bone and Bones/blood supply/injuries/metabolism, Cultured Cells, Endothelial Growth Factors/pharmacology, Femoral Fractures/physiopathology, Fracture Healing/drug effects, Humans, Inbred C57BL Mice, Lymphokines/pharmacology, Male, Mice, Osteoblasts/drug effects/physiology, Physiologic Neovascularization/drug effects, Rabbits, Radius/injuries, Tibia/injuries/radiography, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors, X-Ray Computed Tomography