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Yoo AJ, Sheth KN, Kimberly WT, Chaudhry ZA, Elm JJ, Jacobson S, Davis SM, Donnan GA, Albers GW, Stern BJ, González RG. Validating imaging biomarkers of cerebral edema in patients with severe ischemic stroke. J Stroke Cerebrovasc Dis. August 2013;22(6):742-749.

Full Text – Open Access

Publication Date
August 2013

How Analyze was Used
“DWI lesion volumes at baseline and day 3–5 were measured by two independent readers using standard planimetric software (Analyze 7.0…). The mean volumes were subsequently used to identify patients for the present study.”

Keywords
Adult
Aged
Aged, 80 and over
Biomarker Subject Codes 44 and 45
Brain Edema/diagnosis/drug therapy/pathology
Brain Ischemia/diagnosis/drug therapy/pathology
Cerebral Ventricles/drug effects/pathology
Cerebrum/drug effects/pathology
Disability Evaluation
Disease Progression
Female
Fibrinolytic Agents/administration & dosage
Humans
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Predictive Value of Tests
Prognosis
Prospective Studies
Reproducibility of Results
Risk Factors
Severity of Illness Index
Stroke/diagnosis/drug therapy/pathology
Thrombolytic Therapy
Time Factors

Author Affiliation(s)
Department of Radiology, Massachusetts General Hospital, Boston, MA, US. (AJY, ZAC, RGG)

Department of Neurology, Massachusetts General Hospital, Boston, MA, US. (WTK)

Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, US. (KNS, BJS)

Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC, US. (JJE)

Remedy Pharmaceuticals, New York, NY, US. (SJ)

Department of Medicine and Neurology at The Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia. (SMD)

Florey Neuroscience Institute, The University of Melbourne, Parkville, Victoria, Australia. (GAD)

Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford, CA, US. (GWA)

ID# 188

Tags: Adult, Aged, Aged_80 and over, Biomarker Subject Codes 44 and 45, Brain Edema/diagnosis/drug therapy/pathology, Brain Ischemia/diagnosis/drug therapy/pathology, Cerebral Ventricles/drug effects/pathology, Cerebrum/drug effects/pathology, Disability Evaluation, Disease Progression, Female, Fibrinolytic Agents/administration & dosage, Humans, Magnetic Resonance Imaging (MRI), Male, Middle Aged, Predictive Value of Tests, Prognosis, Prospective Studies, Reproducibility of Results, Risk Factors, Severity of Illness Index, Stroke/diagnosis/drug therapy/pathology, Thrombolytic Therapy, Time Factors