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Le Masurier M, Houston G, Cowen P, Grasby P, Sharp T, Hume S. Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [¹¹C]raclopride in striatum in vivo: a rat PET study. Synapse. February 2004;51(2):151-157.

Publication Date
February 2004

How Analyze was Used
“Scan sinograms were reconstructed into 0.5 mm cubic voxels (with a Hamming filter, 0.6 cut-off) and transferred into ANALYZE-AVW software (Robb, 2001).”

Keywords
Amino Acids/pharmacology
Amphetamine/pharmacology
Analysis of Variance
Animals
Brain Mapping
Carbon Isotopes/pharmacokinetics
Carbon Radioisotopes
Central Nervous System Stimulants/pharmacology
Cerebellum/drug effects/radionuclide imaging
Corpus Striatum/drug effects/radionuclide imaging
Dopamine Antagonists/pharmacokinetics
Male
Models, Animal
Raclopride/pharmacokinetics
Rats
Rats, Sprague-Dawley
Tomography, Emission-Computed
Tyrosine/metabolism

Author Affiliation(s)
University Department of Pharmacology, Mansfield Road, Oxford OX1 3QT, UK. (MLM, TS)

MRC PET Psychiatry, Cyclotron Building, Hammersmith Hospital, London W12 0NN, UK. (GH, PG)

University Department of Psychiatry, Warneford Hospital, Oxford, UK. (PC)

IRSL, Cyclotron Building, Hammersmith Hospital, London, W12 0NN, UK. (SH)

ID# 2321

Tags: Amino Acids/pharmacology, Amphetamine/pharmacology, Analysis of Variance, Animal Models, Animals, Brain Mapping, Carbon Isotopes/pharmacokinetics, Carbon Radioisotopes, Central Nervous System Stimulants/pharmacology, Cerebellum/drug effects/radionuclide imaging, Corpus Striatum/drug effects/radionuclide imaging, Dopamine Antagonists/pharmacokinetics, Emission-Computed Tomography, Male, Raclopride/pharmacokinetics, Rats, Sprague-Dawley Rats, Tyrosine/metabolism