AnalyzeDirect Lixia Zhang et al. Tristetraprolin regulates the skeletal phenotype and osteoclastogenic potential through monocytic myeloid-derived suppressor cells The FASEB Journal.
Publication Date
December 1, 2023
How Analyze was Used
“Three-dimensional images were generated, reconstructed, and analyzed using AnalyzePro software (AnalyzeDirect, Inc., Overland Park, KS). These images were rotated with a standard orientation and threshold to discern mineralized and non-mineralized tissue. Regions of interest (ROI) in the proximal portion of the tibia started from the proximal border of the growth plate. Two ROIs of 960 μm each (0–960 and 1200–2160 μm from the growth plate border) were selected, and the proximal part was used for trabecular bone analysis, and the distal part of ROI was used for cortical bone analysis. All images were analyzed individually, and the ROI was applied to each image.”
Keywords
Myeloid-derived suppressor cells, Osteoclasts, Osteoimmunology, Transcriptome, Tristetraprolin
Author Affiliation(s)
University at Buffalo, Buffalo, New York, USA
