AnalyzeDirect Thöne-Reineke C, Neumann C, Namsolleck P, Schmerbach K, Krikov M, Schefe JH, Lucht K, Hörtnagl H, Godes M, Müller S, Rumschüssel K, Funke-Kaiser H, Villringer A, Steckelings UM, Unger T. The ß-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke. J Hypertens. December 2008;26(12):2426-2435.
Full Text – Open Access
Publication Date
December 2008
How Analyze was Used
“Calculation of lesion volume was carried out with the program Analyze 5.0 (AnalyzeDirect, Inc., Lenexa, Kansas, USA).”
Keywords
Animals
Anti-Bacterial Agents/pharmacology
Body Temperature/physiology
Brain/blood supply
Brain Infarction/pathology
Ceftriaxone/pharmacology
Cerebrovascular Disorders/complications
Disease Models, Animal
Excitatory Amino Acid Transporter 2/metabolism
Glutamic Acid/metabolism
Interleukin-6/metabolism
Male
Nerve Growth Factors/metabolism
RNA, Messenger/metabolism
Rats
Rats, Wistar
Regional Blood Flow/drug effects/physiology
Stroke/etiology/metabolism/mortality
Survival Rate
Author Affiliation(s)
Center for Cardiovascular Research (CCR)/Institute of Pharmacology, Germany. (CTR, CN, PN, KS, MK, JHS, KL, HH, KR, HF-K, UMS, TU)
Institute of Physiology, Germany. (BG)
Clinic and Polyclinic for Neurology, Charité – Universitätsmedizin Berlin, Berlin, Germany. (SM, AV)
ID# 1412
Tags: Animal Disease Models, Animals, Anti-Bacterial Agents/pharmacology, Body Temperature/physiology, Brain Infarction/pathology, Brain/blood supply, Ceftriaxone/pharmacology, Cerebrovascular Disorders/complications, Excitatory Amino Acid Transporter 2/metabolism, Glutamic Acid/metabolism, Interleukin-6/metabolism, Male, Messenger RNA/metabolism, Nerve Growth Factors/metabolism, Rats, Regional Blood Flow/drug effects/physiology, Stroke/etiology/metabolism/mortality, Survival Rate, Wistar Rats