AnalyzeDirect Goodrich-Hunsaker NJ, Gilbert PE, Hopkins RO. The role of the human hippocampus in odor-place associative memory. Chem Senses. July 2009;34(6):513-521.
Full Text – Open Access
Publication Date
July 2009
How Analyze was Used
“Proton density and T2 axial dual-echo images were quantified as described by Blatter et al. (1995) using the software ANALYZE 5.0/6.0 … The original 16-bit images were converted to 8-bit images in ANALYZE file format. A multistep volume analysis was then performed using several image-processing tools available in ANALYZE. Regions of cerebral spinal fluid (CSF), white matter, and gray matter were defined by the user and plotted in a 2-dimensional feature space. Quantitative MR analyses of the temporal lobe gyri were performed as per the methods described previously (Bigler et al. 1997, 2002).
“Quantitative MR analyses of brain structures were performed on all amnesic subjects as per the methods described previously (Bigler et al. 1997, 2002). Volumes of the following brain structures were determined by using the region of interest (ROI) feature of ANALYZE that yields a count of gray matter, white matter, and CSF: lateral ventricles, third ventricle, fourth ventricle, temporal horns, total brain volume, and CSF.”
Keywords
Adult
Amnesia/physiopathology
Animals
Behavior
Female
Hippocampus/physiology
Humans
Magnetic Resonance Imaging (MRI)
Male
Memory
Middle Aged
Neuropsychological Tests
Odors
Rats
Recognition (Psychology)
Smell/physiology
Author Affiliation(s)
Department of Physiology and Developmental Biology, Brigham Young University, 574 John A. Widtsoe Building, Provo, UT 84602, US. (NJG-H)
Neuroscience Center, Brigham Young University, 1001 Spenser W. Kimball Tower, Provo, UT 84602, US. (NJG-H, RDH)
Department of Psychology, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, US. (PEG)
San Diego State University – University of California San Diego Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, US. (PEG)
Psychology Department, Brigham Young University, 1082 Spencer W. Kimball Tower, Provo, UT 84602, US. (RDH)
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, 8th Avenue and C Street, Salt Lake City, UT 84143, US. (RDH)
Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, 5121 South Cottonwood Street, Murray, UT 84157, US. (RDH)
ID# 1232
Tags: Adult, Amnesia/physiopathology, Animals, Behavior, Female, Hippocampus/physiology, Humans, Magnetic Resonance Imaging (MRI), Male, Memory, Middle Aged, Neuropsychological Tests, Odors, Rats, Recognition (Psychology), Smell/physiology