Tag Archives: hypophosphatasia

Effects of comorbid chronic kidney disease on late-onset hypophosphatasia mice under treatment with asfotase alfa

Cintia Tokuhara et al. Effects of comorbid chronic kidney disease on late-onset hypophosphatasia mice under treatment with asfotase alfa JBMR Plus. Publication Date April 17, 2026 How Analyze was Used “Reconstructed DICOM files were exported and analyzed using Analyze version 14.0 (AnalyzeDirect, Overland Park, KS, USA).” Keywords Preclinical model, Mouse, Loss-of-function, Hypophosphatasia, Chronic kidney disease,…

Alpl Ablation in Dental Epithelium Disrupts Ameloblasts and Incisor Enamel Mineralization in Male Mice

Fatma F Mohamed et al. Alpl Ablation in Dental Epithelium Disrupts Ameloblasts and Incisor Enamel Mineralization in Male Mice JBMR Plus. Publication Date November 10, 2025 How Analyze was Used “Analysis was performed using Analyze 14.0 (version 1.0; AnalyzeDirect, Overland Park, KS, USA). Femur trabecular and cortical bone regions of interest (ROIs) were segmented at…

Dentoalveolar defects and impaired alveolar bone healing in a neural crest directed conditional knockout mouse model of hypophosphatasia

F.F. Mohamed et al. Dentoalveolar defects and impaired alveolar bone healing in a neural crest directed conditional knockout mouse model of hypophosphatasia Bone. Publication Date May 19, 2025 How Analyze was Used “Reconstructed images were calibrated to five known densities of hydroxyapatite and analyzed using Analyze 14.0 (AnalyzeDirect, Overland Park, KS, USA).” Keywords Mineralized tissue/development,…

Dentoalveolar Defects of Hypophosphatasia are Recapitulated in a Sheep Knock-In Model

Fatma F. Mohamed et al. Dentoalveolar Defects of Hypophosphatasia are Recapitulated in a Sheep Knock-In Model Journal of Bone and Mineral Research. Publication Date August 3, 2022 How Analyze was Used “DICOM files of teeth were reconstructed, calibrated to five known densities of hydroxyapatite (mg/cm3 HA), and analyzed using AnalyzePro version 1.0 (AnalyzeDirect). Orientation and…

Genetic engineering a large animal model of human hypophosphatasia in sheep

Diarra K. Williams et al. Genetic engineering a large animal model of human hypophosphatasia in sheep. Scientific Reports. Publication Date November 16 2018 How Analyze was Used “For dental analyses, CT image stacks (DICOM) were exported as IMA files and reconstructed in AnalyzePro 1.0 (AnalyzeDirect, Overland Park, KS, USA). Sheep mandibles were oriented to a…