Tag Archives: Corpus Striatum/drug effects/radionuclide imaging

Further evaluation of the carbon11-labeled D2/3 agonist PET radiotracer PHNO: reproducibility in tracer characteristics and characterization of extrastriatal binding

Egerton A, Hirani E, Ahmad R, Turton DR, Brickute D, Rosso L, Howes OD, Luthra SK, Grasby PM. Further evaluation of the carbon11-labeled D2/3 agonist PET radiotracer PHNO: reproducibility in tracer characteristics and characterization of extrastriatal binding. Synapse. April 2010;64(4):301-312. Full Text – Open Access Publication Date April 2010 How Analyze was Used “Image volumes…

Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers

Mehta MA, Montgomery AJ, Kitamura Y, Grasby PM. Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers. Psychopharmacology (Berl). January 2008;196(1):157-165. Publication Date January 2008 How Analyze was Used “An ROI for the region of the substantia nigra was based on a template developed in…

Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [11C]raclopride in striatum in vivo: a rat PET study

Le Masurier M, Houston G, Cowen P, Grasby P, Sharp T, Hume S. Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [11C]raclopride in striatum in vivo: a rat PET study. Synapse. February 2004;51(2):151-157. Publication Date February 2004 How Analyze was Used “Scan sinograms were reconstructed into 0.5 mm cubic voxels (with a Hamming filter, 0.6…