Tag Archives: Carbon Radioisotopes/diagnostic use

Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil

Langer O, Bauer M, Hammers A, Karch R, Pataraia E, Koepp MJ, Abrahim A, Luurtsema G, Brunner M, Sunder-Plassmann R, Zimprich F, Joukhadar C, Gentzsch S, Dudczak R, Kletter K, Muller M, Baumgartner C. Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil. Epilepsia. September 2007;48(9):1774-1784. Full Text – Open Access Publication…

Extrastriatal D2 and striatal D2 receptors in depressive illness: pilot PET studies using [11C]FLB 457 and [11C]raclopride

Montgomery AJ, Stokes P, Kitamura Y, Grasby PM. Extrastriatal D2 and striatal D2 receptors in depressive illness: pilot PET studies using [11C]FLB 457 and [11C]raclopride. J Affect Disord. August 2007;101(1-3):113-122. Publication Date August 2007 How Analyze was Used “ROI from the right and left hemispheres were combined. Tissue TAC were generated by overlaying these ROI…

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study

Edison P, Archer HA, Hinz R, Hammers A, Pavese N, Tai YF, Hotton G, Cutler D, Fox N, Kennedy A, Rossor M, Brooks DJ. Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study. Neurology. February 2007;68(7):501-508. Publication Date February 2007 How Analyze was Used “Mean cerebellar tracer uptake was then calculated…

High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO

Willeit M, Ginovart N, Kapur S, Houle S, Hussey D, Seeman P, Wilson AA. High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO. Biol Psychiatry. March 2006;59(5):389-394. Publication Date March 2006 How Analyze was Used “Each subject had a brain MRI examination. MRI scans were co-registered to the PET scan using…

Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study

Bouvard S, Costes N, Bonnefoi F, Lavenne F, Mauguière F, Delforge J, Ryvlin P. Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study. Brain. June 2005;128(Pt 6):1330-1343. Full Text – Open Access Publication Date June 2005 How Analyze was Used “We judged the quality of the co-registration procedure by looking at the…

2-[11C]thymidine positron emission tomography reproducibility in humans

Wells P, Gunn RN, Steel C, Ranicar AS, Brady F, Osman S, Jones T, Price P. 2-[11C]thymidine positron emission tomography reproducibility in humans. Clin Cancer Res. June 2005;11(12):4341-4347. Full Text – Open Access Publication Date June 2005 How Analyze was Used “Regions of interest were drawn by hand, guided by diagnostic imaging, and defined using…

Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: small animal PET and gene expression studies

Hirani E, Sharp T, Sprakes M, Grasby P, Hume S. Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: small animal PET and gene expression studies. Synapse. December 2003;50(3):251-260. Publication Date December 2003 How Analyze was Used “Data were transferred into ANALYZE-AVW imaging software (Robb, 2001) and a standard VOI template, drawn from…

Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study

Montgomery AJ, McTavish SF, Cowen PJ, Grasby PM. Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study. Am J Psychiatry. October 2003;160(10):1887-1889. Full Text – Open Access Publication Date October 2003 How Analyze was Used “Time activity curves for individual regions were generated by using image analysis software (Analyze…

Assessment of proliferation in vivo using 2-[11C]thymidine positron emission tomography in advanced intra-abdominal malignancies

Wells P, Gunn RN, Alison M, Steel C, Golding M, Ranicar AS, Brady F, Osman S, Jones T, Price P. Assessment of proliferation in vivo using 2-[11C]thymidine positron emission tomography in advanced intra-abdominal malignancies. Cancer Res. October 2002;62(20):5698-5702. Full Text – Open Access Publication Date October 2002 How Analyze was Used “ROIs were defined using…

In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion

Cagnin A, Myers R, Gunn RN, Lawrence AD, Stevens T, Kreutzberg GW, Jones T, Banati RB. In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion. Brain. October 2001;124(Pt 10):2014-2027. Full Text – Open Access Publication Date October 2001 How Analyze was Used “For…