Tag Archives: Apoptosis

Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer

S. R. Dubash et al. Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer. European Journal of Nuclear Medicine and Molecular Imaging. Publication Date September 27 2018 How Analyze was Used “In both studies, all VOIs were also outlined on fused PET/ CT images to create binary object masks…

Effects of single injection of local anesthetic agents on intervertebral disc degeneration: ex vivo and long-term in vivo experimental study

Iwasaki K, Sudo H, Yamada K, Higashi H, Ohnishi T, Tsujimoto T, Iwasaki N. Effects of single injection of local anesthetic agents on intervertebral disc degeneration: ex vivo and long-term in vivo experimental study. PLoS One. October 2014;9(10):e109851. Full Text – Open Access Publication Date October 2014 How Analyze was Used “Quantitative analysis of the…

Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function

Li ZL, Ebrahimi B, Zhang X, Eirin A, Woollard JR, Tang H, Lerman A, Wang SM, Lerman LO. Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function. Am J Physiol Heart Circ Physiol. April 2014;306(7):H1087-1101. Publication Date April 2014 How Analyze was Used “Images were analyzed…

TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model–evaluation by MRI

Komar-Stossel C, Gross E, Dery E, Corchia N, Meir K, Fried I, Abramovitch R. TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model–evaluation by MRI. PLoS One. March 2014;9(3):e90224. Full Text – Open Access Publication Date March 2014 How Analyze was Used “Tumor volume was manually assessed from…

Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension

Eirin A, Williams BJ, Ebrahimi B, Zhang X, Crane JA, Lerman A, Textor SC, Lerman LO. Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension. J Hypertens. January 2014;32(1):154-165. Full Text – Open Access Publication Date January 2014 How Analyze was Used “Left ventricular muscle mass (LVMM), cardiac output, early (E)…

Anti-tumor activity of the IGF-1R kinase inhibitor PQIP in colon cancer

Chowdhury S, Dominguez I, Sharratt E, Spernyak J, Brattain MG, Ashwani R. Anti-tumor activity of the IGF-1R kinase inhibitor PQIP in colon cancer. Clin Exp Pharmacol. June 2013;S4(005). Full Text – Open Access Publication Date June 2013 How Analyze was Used “Tumor volumes were calculated by manually drawing regions of interest (ROI’s) over the tumors…

Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis

Eirin A, Zhu XY, Krier JD, Tang H, Jordan KL, Grande JP, Lerman A, Textor SC, Lerman LO. Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis. Stem Cells. May 2012;30(5):1030-1041. Full Text – Open Access Publication Date May 2012 How Analyze was Used “Images were…

Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure

Favreau F, Zhu XY, Krier JD, Lin J, Warner L, Textor SC, Lerman LO. Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure. Kidney Int. December 2010;78(11):1110-1118. Full Text – Open Access Publication Date December 2010 How Analyze was Used “MDCT images were reconstructed and displayed with the…

Hepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease

Stroope A, Radtke B, Huang B, Masyuk T, Torres V, Ritman E, LaRusso N. Hepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease. Am J Pathol. March 2010;176(3):1282-1291. Full Text – Open Access Publication Date March 2010 How Analyze was Used “Specimens were scanned using a micro-computed tomography (CT) scanner….

Redox-sensitive myocardial remodeling and dysfunction in swine diet-induced experimental hypercholesterolemia

Zhu XY, Daghini E, Rodriguez-Porcel M, Chade AR, Napoli C, Lerman A, Lerman LO. Redox-sensitive myocardial remodeling and dysfunction in swine diet-induced experimental hypercholesterolemia. Atherosclerosis. July 2007;193(1):62-69. Publication Date July 2007 How Analyze was Used “During suspended respiration, an eight-level ECG-triggered cine sequence with 8 mm-thick tomographic slices was obtained. The images were reconstructed and…