SPECT imaging with the D4 receptor antagonist L-750,667 in nonhuman primate brain

Staley JK, Tamagnan G, Baldwin RM, Fujita M, Al Tikriti MS, Eshima L, Thornback J, Roe D, Lu L, Seibyl JP, Innis RB. SPECT imaging with the D₄ receptor antagonist L-750,667 in nonhuman primate brain. Nucl Med Biol. August 2000;27(6):547-556.

Publication Date
August 2000

How Analyze was Used
“The skull was stripped from the MRI using the image edit function in Analyze 7.5.5.”

Keywords
Animals
Basal Ganglia/metabolism/radionuclide imaging
Binding, Competitive/drug effects
Brain/metabolism/radionuclide imaging
Brain Stem/metabolism/radionuclide imaging
Cerebellum/metabolism/radionuclide imaging
Dopamine Antagonists/pharmacokinetics
Dopamine D2 Receptor Antagonists
Frontal Lobe/metabolism/radionuclide imaging
Gyrus Cinguli/metabolism/radionuclide imaging
Imidazoles/pharmacology
Iodine Radioisotopes
Occipital Lobe/metabolism/radionuclide imaging
Organ Specificity
Papio
Parietal Lobe/metabolism/radionuclide imaging
Pyridines/blood/pharmacokinetics
Pyrimidines/pharmacology
Pyrroles/blood/pharmacokinetics
Receptors, Dopamine D4
Temporal Lobe/metabolism/radionuclide imaging
Tissue Distribution
Tomography, Emission-Computed, Single-Photon (SPECT)/methods

Author Affiliation(s)
Department of Psychiatry, Yale University School of Medicine & VA Connecticut Healthcare System, West Haven, CT, US. (JKS, GT, RMB, MF, MSAT, JPS, RBI)

Department of Pharmacology, Yale University School of Medicine & VA Connecticut Healthcare System, West Haven, CT, US. (RBI)

Department of Diagnostic Radiology, Yale University School of Medicine & VA Connecticut Healthcare System, West Haven, CT, US. (JPS)

Resolution Pharmaceuticals, Mississauga, Ontario, Canada. (LE, JT, DR, LL)

ID# 2834

AnalyzeDirect

Analyze Publications Database

SPECT imaging with the D₄ receptor antagonist L-750,667 in nonhuman primate brain