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Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation

Philipp Jordan et al. Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation Plos ONE.

Publication Date
February 6, 2023

How Analyze was Used
“Calculation of lesion volume was carried out with the program Analyze 10.0 (AnalyzeDirect, Inc., Overland Park, USA). The hyper intense ischemic areas in axial T2-weighted images were assigned with a region of interest tool. This enables threshold-based segmentation by connecting all pixels within a specified threshold range about the selected seed pixel and results in a 3D object map of the whole stroke region. Further, the total volume of the whole object map was automatically calculated.”

Keywords
Small molecule inhibiting microglial nitric oxide, neuroinflammation

Author Affiliation(s)
Washington University School of Medicine, St. Louis, Missouri, USA

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