AnalyzeDirect Perumal M, Pillai RG, Barthel H, Leyton J, Latigo JR, Forster M, Mitchell F, Jackman AL, Aboagye EO. Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography. Cancer Res. September 2006;66(17):8558-8564.
Full Text – Open Access
Publication Date
September 2006
How Analyze was Used
“The image data-sets obtained were transferred to a SUN workstation … and visualized using the Analyze software (version 6.0).”
Keywords
Animals
Cell Line, Tumor
Cell Membrane/physiology/radionuclide imaging
Fibrosarcoma/radionuclide imaging
Fluorine Radioisotopes
Mice
Neoplasms, Radiation-Induced/radionuclide imaging
Nucleoside Transport Proteins/metabolism
Positron-Emission Tomography (PET)
Thymidylate Synthase/antagonists & inhibitors
Author Affiliation(s)
Molecular Therapy Group, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK. (MP, RGP, HB, JL, JRL, EOA)
Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany. (HB)
Section of Medicine, Institute of Cancer Research, Surrey, UK. (MF, FM, ALJ)
ID# 1898
Tags: Animals, Cell Membrane/physiology/radionuclide imaging, Fibrosarcoma/radionuclide imaging, Fluorine Radioisotopes, Mice, Nucleoside Transport Proteins/metabolism, Positron Emission Tomography (PET), Radiation-Induced Neoplasms/radionuclide imaging, Thymidylate Synthase/antagonists & inhibitors, Tumor Cell Line