AnalyzeDirect Langheinrich AC, Ritman EL. Quantitative imaging of microvascular permeability in a rat model of lipopolysaccharide-induced sepsis: evaluation using cryostatic micro-computed tomography. Invest Radiol. August 2006;41(8):645-650.
Publication Date
August 2006
How Analyze was Used
“Temperature sensors within the chamber were used to control the rate of inflow of cold nitrogen gas so as to maintain the specimen temperature within ±1°C off the desired temperature. The resulting 3D images (18-μm cubic voxels) were displayed at 16-bit gray scale and analyzed using image analysis software (Analyze 6.0).”
Keywords
Animals
Capillary Permeability
Contrast Media/pharmacokinetics
Coronary Vessels/metabolism
Disease Models, Animal
Endothelium, Vascular/pathology
Escherichia coli
Imaging, Three-Dimensional
Intestines/blood supply/metabolism
Kidney/blood supply/metabolism
Lipopolysaccharides/adverse effects
Liver/blood supply/metabolism
Male
Myocardium/metabolism
Rats
Rats, Wistar
Sepsis/etiology/physiopathology
Silicone Elastomers
Tomography, X-Ray Computed/methods
Author Affiliation(s)
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (ACL)
ID# 1916
Tags: Animal Disease Models, Animals, Capillary Permeability, Contrast Media/pharmacokinetics, Coronary Vessels/metabolism, Escherichia coli, Intestines/blood supply/metabolism, Kidney/blood supply/metabolism, Lipopolysaccharides/adverse effects, Liver/blood supply/metabolism, Male, Myocardium/metabolism, Rats, Sepsis/etiology/physiopathology, Silicone Elastomers, Three-Dimensional Imaging, Vascular Endothelium/pathology, Wistar Rats, X-Ray Computed Tomography/methods