AnalyzeDirect Berry LR, Barck KH, Go MA, Ross J, Wu X, Williams SP, Gogineni A, Cole MJ, Van Bruggen N, Fuh G, Peale F, Ferrara N, Ross S, Schwall RH, Carano RAD. Quantification of viable tumor microvascular characteristics by multispectral analysis. Magn Reson Med. July 2008;60(1):64-72.
Publication Date
July 2008
How Analyze was Used
“A ‘brightfield’ reference image was acquired with a 250-ms exposure. Tumor borders were defined within the reference image with Analyze image analysis software (AnalyzeDirect, Lenexa, KS). Areas of nonviable tumor tissue (skin, subcutaneous adipose, regions of necrosis) visible within the reference image were excluded.”
Keywords
Animals
Antibodies/therapeutic use
Female
Magnetic Resonance Imaging (MRI)/methods
Mice
Mice, Nude
Microcirculation/anatomy & histology
Neoplasms, Experimental/blood supply
Tissue Survival
Vascular Endothelial Growth Factor A/immunology
Author Affiliation(s)
Department of Translational Oncology, Genentech, South San Francisco, CA, US. (LRB, MAG, SR, RHS)
Department of Tumor Biology and Angiogenesis, Genentech, South San Francisco, CA, US. (KHB, JR, SPW, AG, MJC, NVB, RADC)
Ferrara Lab, Genentech, South San Francisco, CA, US. (XW, NF)
Department of Protein Engineering, Genentech, South San Francisco, CA, US. (GF)
Department of Pathology, Genentech, South San Francisco, CA, US. (FP)
ID# 1524
Tags: Animals, Antibodies/therapeutic use, Experimental Neoplasms/blood supply, Female, Magnetic Resonance Imaging (MRI)/methods, Mice, Microcirculation/anatomy & histology, Nude Mice, Tissue Survival, Vascular Endothelial Growth Factor A/immunology