Analyze Publications Database

Premature aging in mice with error-prone protein synthesis

Dimitri Shcherbakov et al. Premature aging in mice with error-prone protein synthesis Science Advances.

Publication Date
March 2, 2022

How Analyze was Used
“We performed trimonthly quantitative assessments of body composition in conscious male mice with a body composition analyzer (EchoMRI-500, EchoMRI LLC, Houston, TX, USA) starting at the age of 3 months. In addition, at 16 months of age, the distribution of body fat was analyzed using micro-CT imaging (Quantum Fx, PerkinElmer, Waltham, MS, USA). Animals were briefly anesthetized with gas anesthesia, whole-body scans were performed at 50 kV/160 mAs, and the body segment containing the lumbar vertebrae L1 to L5 was then analyzed for fat distribution using Analyze 12.0 (AnalyzeDirect, Overland Park, KS, USA).”

Keywords
Premature aging, Error-prone protein synthesis, Mice

Author Affiliation(s)
University of Zurich, Zurich, Switzerland.

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