AnalyzeDirect Marik J, Ogasawara A, Martin-McNulty B, Ross J, Flores JE, Gill HS, Tinianow JN, Vanderbilt AN, Nishimura M, Peale F, Pastuskovas C, Greve JM, van Bruggen N, Williams SP. PET of glial metabolism using 2-18F-fluoroacetate. J Nucl Med. June 2009;50(6):982-990.
Full Text – Open Access
Publication Date
June 2009
How Analyze was Used
“The PET images were acquired on microPET Focus 120 scanners (Siemens Preclinical Solutions)…. Measurements were obtained with region-of-interest analysis using ASIPro software or Analyze 8.1 (Biomedical Imaging Resources). The tissue uptake for dynamic scans was calculated as average uptake over the last 20 min of the scan.”
Keywords
Animals
Brain Ischemia/metabolism
Fluorine Radioisotopes/diagnostic use
Fluoroacetates/diagnostic use
Fluorodeoxyglucose F18/diagnostic use
Glioblastoma/metabolism
Hypoxia-Ischemia, Brain/metabolism
Male
Mice
Mice, Inbred C57BL
Neuroglia/metabolism
Positron-Emission Tomography (PET)/methods
Radiopharmaceuticals/diagnostic use
Rats
Rats, Wistar
Author Affiliation(s)
Biomedical Imaging, Genentech Inc., South San Francisco, California. (JM, AO, BM-M, JR, JEF, HSG, JNT, ANV, JMG, NB, SPW)
Department of Tumor Biology and Angiogenesis, Genentech Inc., South San Francisco, California. (MN)
Research Pathology, Genentech Inc., South San Francisco, California. (FP)
Early Development PKPD, Genentech Inc., South San Francisco, California. (CP)
ID# 1239
Tags: Animals, Brain Hypoxia-Ischemia/metabolism, Brain Ischemia/metabolism, Fluorine Radioisotopes/diagnostic use, Fluoroacetates/diagnostic use, Fluorodeoxyglucose F18/diagnostic use, Glioblastoma/metabolism, Inbred C57BL Mice, Male, Mice, Neuroglia/metabolism, Positron-Emission Tomography (PET)/methods, Radiopharmaceuticals/diagnostic use, Rats, Wistar Rats