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Broggini T, Wüstner M, Harms C, Stange L, Blaes J, Thomé C, Harms U, Mueller S, Weiler M, Wick W. NDRG1 overexpressing glioma are characterized by reduced tumor vascularisation and resistance to antiangiogenic treatment. Cancer Lett. August 2015.

Publication Date
August 2015

How Analyze was Used
“For T1w contrast 100 µl Gd-DTPA (Magnevist …) 0.5 mmol/kg were injected intra venous. The calculation of tumor volumes was carried out with Analyze 10.0.”

Keywords
Angiogenesis Inhibitors
Glioma
Mice
N-myc downstream-regulated gene 1 protein
NF-kappa B
Response Elements
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factor AP-1
Tumor Burden
Tumor Necrosis Factor Ligand Superfamily Member 15
Up-Regulation
Vascular Resistance

Author Affiliation(s)
Department of Neurosurgery, Neurochirurgische Klinik – Universitätsmedizin Charite, Augustenburger Platz 1, 13353 Berlin, Germany. (TB, MW, LS, UH, SM, PV, MC)

Department of Experimental Neurology, Universitätsmedizin Charite, Berlin, Germany. (CH)

Department of Neurooncology, Neurology Clinic and National Center for Tumor Diseases, Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), University of Heidelberg and German Cancer Consortium (DKTK), Germany. (JB, CT, MW, WW)

ID# 3150

Tags: Angiogenesis Inhibitors, Glioma, Mice, N-myc downstream-regulated gene 1 protein, NF-kappa B, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factor AP-1, Tumor Burden, Tumor Necrosis Factor Ligand Superfamily Member 15, Up-Regulation, Vascular Resistance