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Mitochondrial DNA and gastrointestinal motor and sensory functions in health and functional gastrointestinal disorders

Camilleri M, Carlson P, Zinsmeister AR, McKinzie S, Busciglio I, Burton D, Zaki EA, Boles RG. Mitochondrial DNA and gastrointestinal motor and sensory functions in health and functional gastrointestinal disorders. Am J Physiol Gastrointest Liver Physiol. March 2009;296(3):G510-516.

Full Text – Open Access

Publication Date
March 2009

How Analyze was Used
“The stomach was identified in the transaxial images and separated from background with a semiautomated segmentation algorithm using the AVW 3.0 … image processing libraries. The primary endpoints were fasting and postprandial gastric volume.”

Keywords
Adult
Constipation/epidemiology/genetics/physiopathology
DNA, Mitochondrial/genetics
Dyspepsia/epidemiology/genetics/physiopathology
Enteric Nervous System/physiology
Gastrointestinal Diseases/epidemiology/genetics/physiopathology
Gastrointestinal Motility/genetics
Genetic Predisposition to Disease/epidemiology
Haplotypes
Humans
Irritable Bowel Syndrome/epidemiology/genetics/physiopathology
Middle Aged
Motor Neurons/physiology
Phenotype
Polymorphism, Single Nucleotide
Risk Factors
Sensory Receptor Cells/physiology

Author Affiliation(s)
Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), College of Medicine, Mayo Clinic, Rochester, MN, US. (MC. PC, SM, IB, DB)

Department of Health Sciences Research, Division of Biostatistics, College of Medicine, Mayo Clinic, Rochester, MN, US. (ARZ)

Division of Medical Genetics and the Saban Research Institute, Children’s Hospital Los Angeles, CA, US. (EAZ, RCB)

Division of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, US. (RCB)

ID# 1319

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