AnalyzeDirect May Zaw Thin et al. Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice Nature Protocols .
Publication Date
December 9, 2022
How Analyze was Used
“Generally, there are two types of tumor volume analysis that can be performed: the direct measurement of individual tumor volume or the indirect quantification of tumor growth based on loss of air (healthy lung) volume, depending on the radiological phenotype of the tumors and the research questions being asked. Our analysis pipeline is based mainly on the semiautomatic segmentation of images following the application of an intensity threshold value and the selection of regions of interests and image processing; however, the automated segmentation steps and analysis of lung volume with the Analyze software (AnalyzeDirect) use the surrounding organs as calibrators.”
Keywords
Cancer imaging, X-ray tomography, MicroCT imaging, Pulmonary nodules, mice
Author Affiliation(s)
The Francis Crick Institute, London, UK
