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Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer

Bhattacharya A, Turowski SG, San Martin ID, Rajput A, Rustum YM, Hoffman RM, Seshadri M. Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer. Anticancer Res. February 2011;31(2):387-393.

Full Text – Open Access

Publication Date
February 2011

How Analyze was Used
“Image processing and analysis were carried out using commercially available software (ANALYZE PC, Version 7.0.”

Keywords
Adenocarcinoma/blood supply/drug therapy/pathology
Animals
Colonic Neoplasms/blood supply/drug therapy/pathology
Cysteine/analogs & derivatives/pharmacology
Diagnostic Imaging/methods
Female
Green Fluorescent Proteins/analysis/metabolism
Humans
Magnetic Resonance Imaging (MRI)/methods
Mice
Mice, Nude
Microvessels/drug effects/metabolism
Neovascularization, Pathologic/drug therapy/pathology
Organoselenium Compounds/pharmacology
Random Allocation
Selenocysteine/analogs & derivatives
Xenograft Model Antitumor Assays

Author Affiliation(s)
Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, US. (AR)

Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, US. (SGT, MS)

Department of Surgical Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, US. (IDSM)

Department of Surgery, Division of Surgical Oncology, University of New Mexico, Albuquerque, NM, US. (AR)

AntiCancer Inc., San Diego, California, US. (YMR, RMH)

Department of Surgery, University of California, San Diego, CA, US. (RMH)

ID# 720

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