Simone Rolfes et al. Lentiviral delivery of human erythropoietin attenuates hippocampal atrophy and improves cognition in the R6/2 mouse model of Huntington’s disease. Neurobiology of Disease.
July 20, 2020
How Analyze was Used
“Regions of interest (ROIs) were manually delineated onto T2*-weighted images according to Paxinos and Franklin mouse brain atlas (2007) for the hippocampus, striatum, cortex and corpus callosum using Analyze 10.0 (AnalyzeDirect, Overland Park, KS). The region-specific volume was then automatically quantified.”
Huntington’s disease, Intracerebroventricular, Gene delivery, Transgenic mice, Therapy, Neurodegeneration
Charité, Universitätsmedizin Berlin, Berlin, Germany