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Edrei Y, Gross E, Corchia N, Abramovitch R. Improved efficacy of a novel anti-angiogenic drug combination (TL-118) against colorectal-cancer liver metastases; MRI monitoring in mice. Br J Cancer. August 2012;107(4):658-666.

Full Text – Open Access

Publication Date
August 2012

How Analyze was Used
“The number of tumours per liver and their volumes were assessed from the T2W images using Analyze-7.0.”

Keywords
Angiogenesis Inhibitors/pharmacology/therapeutic use
Animals
Cimetidine/pharmacology/therapeutic use
Colorectal Neoplasms/blood supply/drug therapy/mortality/pathology
Cyclophosphamide/pharmacology/therapeutic use
Diclofenac/pharmacology/therapeutic use
Disease Progression
Drug Combinations
Humans
Liver Neoplasms/drug therapy/metabolism/prevention & control/secondary
Magnetic Resonance Imaging (MRI)
Male
Mice
Nitric Oxide/metabolism
Sulfasalazine/pharmacology/therapeutic use

Author Affiliation(s)
Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel. (YE, NC, RA)

MRI/MRS lab HBRC, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel. (YE, RA)

Department of Pediatric Surgery, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel. (EG)

ID# 487

Tags: Angiogenesis Inhibitors/pharmacology/therapeutic use, Animals, Cimetidine/pharmacology/therapeutic use, Colorectal Neoplasms/blood supply/drug therapy/mortality/pathology, Cyclophosphamide/pharmacology/therapeutic use, Diclofenac/pharmacology/therapeutic use, Disease Progression, Drug Combinations, Humans, Liver Neoplasms/drug therapy/metabolism/prevention & control/secondary, Magnetic Resonance Imaging (MRI), Male, Mice, Nitric Oxide/metabolism, Sulfasalazine/pharmacology/therapeutic use