AnalyzeDirect Sciorati C, Staszewsky L, Zambelli V, Russo I, Salio M, Novelli D, Di Grigoli G, Moresco RM, Clementi E, Latini R. Ibuprofen plus isosorbide dinitrate treatment in the mdx mice ameliorates dystrophic heart structure. Pharmacol Res. July 2013;73:35-43.
Publication Date
July 2013
How Analyze was Used
“Quantification analysis was performed with the Analyse 7.0 software (AnalyzeDirect Inc., Overland Park, KS, United States) using the Region of Interest (ROIs) analysis. At least 10 slices for animal were analysed.”
Keywords
Animals
Anti-Inflammatory Agents, Non-Steroidal/administration & dosage
Cardiac Output
Ibuprofen/administration & dosage
Isosorbide Dinitrate/administration & dosage
Mice
Mice, Inbred mdx
Muscular Dystrophy, Duchenne/drug therapy/pathology/physiopathology
Myocardium/pathology
Nitric Oxide Donors/administration & dosage
Stroke Volume
Ventricular Function, Left/drug effects
Author Affiliation(s)
Division of Regenerative Medicine, Ospedale San Raffaele Scientific Institute, via Olgettina 58, Milan, Italy. (CS)
Department of Cardiovascular Research, IRCCS-Istituto di Ricerche Farmacologiche “Mario Negri”, via Giuseppe La Masa 19, 20156 Milan, Italy. (LS, IR, MS, DM, RL)
Department of Health Science, University of Milano-Bicocca, via Cadore 48, 20900 Monza, Italy. (VZ)
Nuclear Medicine Department and PET Centre, San Raffaele Scientific Institute, Milan, MI, Italy. (GG, RMM)
IBFM-CNR, via F.lli Cervi, 93, Segrate, Milano Italy. (GG, RMM)
Fondazione TECNOMED, Department of Health Sciences, University of Milan-Bicocca, via Cadore 48, 20900 Monza, Italy. (GG, RMM)
Unit of Clinical Pharmacology, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, 20157 Milan, Italy. (EC)
Scientific Institute, IRCCS Eugenio Medea, 23842 Bosisio Parini, Lecco, Italy. (EC)
ID# 361
Tags: Animals, Cardiac Output, Duchenne Muscular Dystrophy/drug therapy/pathology/physiopathology, Ibuprofen/administration & dosage, Inbred mdx Mice, Isosorbide Dinitrate/administration & dosage, Left Ventricular Function/drug effects, Mice, Myocardium/pathology, Nitric Oxide Donors/administration & dosage, Non-Steroidal Anti-Inflammatory Agents/administration & dosage, Stroke Volume