AnalyzeDirect Ellie Fisher1, Diane Austin1, Helen M. Werner1, Ying Ji Chuang1, Edward Bersu2, Houri K. Vorperian1. Hyoid bone fusion and bone density across the lifespan: prediction of age and sex. Forensic Science, Medicine, and Pathology. April 25th, 2016.
Full Text – Open Access
Publication Date
April 2016
How Analyze was Used
“A three-dimensional model of each hyoid bone was generated using Analyze 11.0® software to calculate the bone density in Hounsfield units (HU). Bone density was measured for each individual hyoid bone to contribute to the overall developmental understanding of hyoid bone form and function and more specifically to assess the relationship between bone density and fusion. […] Analyze 11.0® software was used to open the DICOM CT scan files for visualization and three-dimensional (3D) modeling. Axial, sagittal, and coronal views were observed simultaneously to ensure accuracy while inspecting the degree of fusion and while creating the 3D model. Three-dimensional hyoid bone models were created with the Volume Edit tool in Analyze 11.0® software with the standard algorithm in order to calculate bone density. The Volume Edit tool in Analyze allows for slice-by-slice tracing and stacking of the hyoid bone structure from CT images to create a 3D model. The volume threshold was manually adjusted by visual inspection on a per slice basis. Intensity in Hounsfield units (HU), commonly used to measure bone density, was then calculated from the outlined region defined by the 3D model generated using the Region of Interest tool (ROI) within Analyze 11.0®. […] For each hyoid bone, every axial CT slice was visually inspected in the Region of Interest tool in Analyze.”
Keywords
Hyoid bone fusion
Bone density
Forensic science
In vivo
Computed tomography
3D modeling
Author Affiliation(s)
1Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison
2School of Medicine and Public Health, University of Wisconsin-Madison