AnalyzeDirect Wu M, Mazurchuk R, Chaudhary ND, Spernyak J, Veith J, Pera P, Greco W, Hoffman RM, Kobayashi T, Bernacki RJ. High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-ß-D-arabino-pentofuranosyl]-N4-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model. Cancer Res. May 2003;63(10):2477-2482.
Full Text – Open Access
Publication Date
May 2003
How Analyze was Used
“Image analysis and three-dimensional volume rendering of data were performed using AnalyzePC Version 4.0.”
Keywords
Animals
Antineoplastic Agents/pharmacology
Arabinonucleosides/pharmacology
Cell Division/drug effects
Colonic Neoplasms/drug therapy/pathology
Cytosine/analogs & derivatives/pharmacology
Deoxycytidine/analogs & derivatives/pharmacology
Female
Fluorouracil/pharmacology
Humans
Liver Neoplasms/pathology/prevention & control/secondary
Magnetic Resonance Imaging (MRI)/methods
Mice
Mice, Nude
Xenograft Model Antitumor Assays
Author Affiliation(s)
Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY14263, US. (MW, NDC, JV, PD, WG, RJB)
Molecular and Cellular Biophysics, Roswell Park Cancer Institute, Buffalo, NY14263, US. (RM, JS)
AntiCancer, Incorporated, San Diego, CA 92111, US. (RMH)
Sankyo Co., Ltd., Tokyo 140-8710, Japan. (TK)
ID# 2413
Tags: Animals, Antineoplastic Agents/pharmacology, Arabinonucleosides/pharmacology, Cell Division/drug effects, Colonic Neoplasms/drug therapy/pathology, Cytosine/analogs & derivatives/pharmacology, Deoxycytidine/analogs & derivatives/pharmacology, Female, Fluorouracil/pharmacology, Humans, Liver Neoplasms/pathology/prevention & control/secondary, Magnetic Resonance Imaging (MRI)/methods, Mice, Nude Mice, Xenograft Model Antitumor Assays