AnalyzeDirect Spernyak JA, White WH, 3rd, Ethirajan M, Patel NJ, Goswami L, Chen Y, Turowski S, Missert JR, Batt C, Mazurchuk R, Pandey RK. Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy. Bioconjug Chem. May 2010;21(5):828-835.
Full Text – Open Access
Publication Date
May 2010
How Analyze was Used
“In vivo MR data sets were processed with commercially available software (Analyze 7.0, AnalyzeDirect, Overland Park, KS) by defining a region of interest (ROI) for tumor, muscle surrounding the backbone, and the 150 μM Gd-DTPA calibration standards.”
Keywords
Animals
Chlorophyll/analogs & derivatives/chemistry/diagnostic use/therapeutic use
Fluorescence
Gadolinium/chemistry/diagnostic use/therapeutic use
Magnetic Resonance Imaging (MRI)/methods
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Neoplasms/diagnosis/drug therapy/pathology
Photochemotherapy/methods
Rats
Author Affiliation(s)
Preclinical Imaging Facility, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (JAS, ST, RM)
PDT Center, Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (WHW, ME, NJP, LG, YC, JRM, CB, RKP)
Molecular Pharmacology and Cancer Therapeutics, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (NJP)
ID# 970
Tags: Animals, Chlorophyll/analogs & derivatives/chemistry/diagnostic use/therapeutic use, Fluorescence, Gadolinium/chemistry/diagnostic use/therapeutic use, Inbred BALB C Mice, Inbred C3H Mice, Magnetic Resonance Imaging (MRI)/methods, Mice, Neoplasms/diagnosis/drug therapy/pathology, Photochemotherapy/methods, Rats