AnalyzeDirect

Willeit M, Ginovart N, Graff A, Rusjan P, Vitcu I, Houle S, Seeman P, Wilson AA, Kapur S. First human evidence of d-amphetamine induced displacement of a D_2/3 agonist radioligand: a [¹¹C]-(+)-PHNO positron emission tomography study. Neuropsychopharmacology. January 2008;33(2):279-289.

Full Text – Open Access

Publication Date
January 2008

How Analyze was Used
“For manual analysis, MRI scans were co-registered to PET scans using Analyze 5.0 software… Regions of Interest for CAU, PUT, VST, GP, and CER were drawn on PD-MRI images and subsequently transferred onto PET images.”

Keywords
Adult
Brain/metabolism/radionuclide imaging
Caudate Nucleus/metabolism/radionuclide imaging
Corpus Striatum/metabolism/radionuclide imaging
Dextroamphetamine/pharmacology
Dopamine Agonists/chemical synthesis/diagnostic use
Female
Globus Pallidus/metabolism/radionuclide imaging
Humans
Male
Oxazines/chemical synthesis/diagnostic use
Positron-Emission Tomography (PET)
Putamen/metabolism/radionuclide imaging

Author Affiliation(s)
Positron Emission Tomography Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada. (MW, NG, AG, PR, IV, SH, AAW, SK)

Department of General Psychiatry, Medical University Vienna, Vienna, Austria. (MW)

Département de Psychiatrie, Unité de Neuroimagerie, Université de Genève, Genève, Switzerland. (NG)

Department of Psychiatry, University of Toronto, Toronto, ON, Canada. (NG, AAW, SK)

Institute of Neurobiology, UNAM, Mexico City, Mexico. (AG)

Department of Pharmacology, University of Toronto, Toronto, ON, Canada. (PS)

ID# 1582

Tags: Adult, Brain/metabolism/radionuclide imaging, Caudate Nucleus/metabolism/radionuclide imaging, Corpus Striatum/metabolism/radionuclide imaging, Dextroamphetamine/pharmacology, Dopamine Agonists/chemical synthesis/diagnostic use, Female, Globus Pallidus/metabolism/radionuclide imaging, Humans, Male, Oxazines/chemical synthesis/diagnostic use, Positron Emission Tomography (PET), Putamen/metabolism/radionuclide imaging