AnalyzeDirect Davies JR, Izquierdo-Garcia D, Rudd JHF, Figg N, Richards HK, Bird JL, Aigbirhio FI, Davenport AP, Weissberg PL, Fryer TD, Warburton EA. FDG-PET can distinguish inflamed from non-inflamed plaque in an animal model of atherosclerosis. Int J Cardiovasc Imaging. January 2010;26(1):41-48.
Publication Date
January 2010
How Analyze was Used
“Quantification of FDG concentration in the PET images was carried out using the software package Analyze … by a blinded observer (DI).”
Keywords
Animals
Aorta/drug effects/radionuclide imaging
Atherosclerosis/drug therapy/etiology/radionuclide imaging
Catheterization
Cholesterol, Dietary
Diagnosis, Differential
Disease Models, Animal
Fluorodeoxyglucose F18/diagnostic use
Heptanoic Acids/pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology
Inflammation/drug therapy/etiology/radionuclide imaging
Macrophages/radionuclide imaging
Male
Positron-Emission Tomography
Predictive Value of Tests
Pyrroles/pharmacology
Rabbits
Radiopharmaceuticals/diagnostic use
Author Affiliation(s)
Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. (JRD, JHFR, NF, PLW)
Wolfson Brain Imaging Centre, University of Cambridge, Addenbrooke’s Hospital, Box 65, Cambridge, CB2 0QQ, UK. (DIG, JLEB, FIA, TDF)
Department of Neurosurgery, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. (HKR)
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. (JLEB, APD)
Clinical Neurosciences, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. (EAW)
ID# 1050
Tags: Animal Disease Models, Animals, Aorta/drug effects/radionuclide imaging, Atherosclerosis/drug therapy/etiology/radionuclide imaging, Catheterization, Dietary Cholesterol, Differential Diagnosis, Fluorodeoxyglucose F18/diagnostic use, Heptanoic Acids/pharmacology, Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology, Inflammation/drug therapy/etiology/radionuclide imaging, Macrophages/radionuclide imaging, Male, Positron-Emission Tomography, Predictive Value of Tests, Pyrroles/pharmacology, Rabbits, Radiopharmaceuticals/diagnostic use