Analyze Publications Database

Executive dysfunction correlates with caudate nucleus atrophy in patients with white matter changes on MRI: a subset of LADIS

Macfarlane MD, Looi JC, Walterfang M, Spulber G, Velakoulis D, Crisby M, Örndahl E, Erkinjuntti T, Garde E, Waldemar G, Wallin A, Wahlund LO. Executive dysfunction correlates with caudate nucleus atrophy in patients with white matter changes on MRI: a subset of LADIS. Psychiatry Res. October 2013;214(1):16-23.

Publication Date
October 2013

How Analyze was Used
“The caudate nuclei were manually traced within ANALYZE 10.0…. through a Region of Interest (ROI) approach on 1.5 T1 MRI scans, by one investigator…blind to clinical data, using a previously published protocol (Looi et al., 2008a).”

Keywords
Aged
Aged, 80 and over
Atrophy/pathology/psychology
Caudate Nucleus/pathology
Cerebrovascular Disease
Executive Function/physiology
Female
Humans
Leukoaraiosis/pathology/psychology
Magnetic Resonance Imaging (MRI)
Male
Mental Recall/physiology
Nerve Fibers, Myelinated/pathology
Neuropsychological Tests
Organ Size

Author Affiliation(s)
Research Centre for the Neurosciences of Ageing, Academic Unit of Psychiatry and Addiction Medicine, Australian National University Medical School, Canberra Hospital, Canberra, ACT, Australia. (MDM, JCLL)

Karolinska Institute, Department of Neurobiology, Care Science and Society, Division of Clinical Geriatrics, Stockholm, Sweden. (JCLL, MC)

Melbourne Neuropsychiatry Centre and University of Melbourne, Melbourne, VIC, Australia. (MW, DV)

Karolinska Institute, Department of Neurobiology, Care Science and Society, Division of Clinical Geriatrics, Stockholm, Sweden. (GS, LOW)

Department of Clinical Science, Intervention and Technology at Karolinska Institute, Division of Medical Imaging and Technology, Stockholm, Sweden. (EÖ)

Department of Radiology, Karolinska University Hospital in Huddinge, Stockholm, Sweden. (EÖ)

Department of Neurological Sciences, University of Helsinki, Finland. (TE)

Department of Neurology, Helsinki University Central Hospital, Finland. (TE)

Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark. (EG)

Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark. (GW)

Institute of Neuroscience and Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden. (AW)

ID# 364

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