Arezoo Daryadel et al. Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice. Scientific Reports.
October 18, 2019
How Analyze was Used
“All images were reconstructed and processed for bone analysis applying a commercially available software (Analyze 12.0, AnalyzeDirect, Inc., Overland Park, KS). A segment of 100 slices proximal to the distal femoral growth plate was analyzed starting where the epiphyseal cap structure completely disappeared. For BMD analysis the average grey level intensity was measured for the diferent calcium hydroxyapatite inserts of the phantom and a linear calibration was derived between grey level intensity and BMD.”
FGF23, Renal mineral handling, Bone mineralization, Erythropoietin overexpression, Transgenic mice
University of Zurich, Zurich, Switzerland