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Effects of cannabis and familial loading on subcortical brain volumes in first-episode schizophrenia

Malchow B, Hasan A, Schneider-Axmann T, Jatzko A, Gruber O, Schmitt A, Falkai P, Wobrock T. Effects of cannabis and familial loading on subcortical brain volumes in first-episode schizophrenia. Eur Arch Psychiatry Clin Neurosci. November 2013;263 Suppl 2:S155-168.

Publication Date
November 2013

How Analyze was Used
“Manual area measurements were obtained by manual tracing of the boundaries using
MRIcro … and for the corpus callosum using additionally the Analyze 3.0 software tools.”

Keywords
Adult
Antipsychotic Agents/pharmacology/therapeutic use
Aspartic Acid/analogs & derivatives/metabolism
Brain/drug effects/pathology
Brain Chemistry
Caudate Nucleus/pathology
Choline/metabolism
Cross-Sectional Studies
Dose-Response Relationship, Drug
Female
Gene-Environment Interaction
Genetic Predisposition to Disease
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging (MRI)
Magnetic Resonance Spectroscopy
Male
Marijuana Abuse/complications/psychology
Psychiatric Status Rating Scales
Putamen/metabolism
Schizophrenia/genetics/pathology
Schizophrenic Psychology
Sex Characteristics
Socioeconomic Factors

Author Affiliation(s)
Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University (LMU) Munich, Nußbaumstraße 7, 80336, Munich, Germany. (BM, AH, TSA, AS, PF)

Westpfal-Klinikum-Kaiserslautern, Teaching Hospital, University of Mainz, Mainz, Germany. (AJ)

Department of Psychiatry and Psychotherapy, Georg-August-University Göttingen, von-Siebold-Str. 5, Göttingen, Germany. (OG, TW)

Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, Rua Dr. Ovidio Pires de Campos 785, São Paulo, SP, 05453-010, Brazil. (AS)

Centre of Mental Health, County Hospitals Darmstadt-Dieburg, Gross-Umstadt, Germany. (TW)

ID# 2711

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