AnalyzeDirect Coplan JD, Fathy HM, Jackowski AP, Tang CY, Perera TD, Mathew SJ, Martinez J, Abdallah CG, Dwork AJ, Pantol G, Carpenter D, Gorman JM, Nemeroff CB, Owens MJ, Kaffman A, Kaufman J. Early life stress and macaque amygdala hypertrophy: preliminary evidence for a role for the serotonin transporter gene. Front Behav Neurosci. October 2014;8:342.
Full Text – Open Access
Publication Date
October 2014
How Analyze was Used
“The axial MPRAGE series were imported into ANALYZE AVW 7.0 … (Robb et al., 1989) software platform and converted to cubic voxel dimensions of 0.44 mm using a cubic spline interpolation algorithm. The amygdalae were manually traced using a detailed set of guidelines developed by Schumann et al. (2004) and adjusted, when necessary, to the bonnet macaque brain morphology using a primate brain atlas (Wu and Robertson, 2000).”
Keywords
Amygdala
Early Life Stress
MRI
Non-Human Primates
Serotonin Transporter Gene
Stress
Author Affiliation(s)
Department of Psychiatry and Behavioral Sciences, State University of New York, Downstate Medical Center, Brooklyn, NY, US. (JDC, HMF)
Departamento de Psiquiatria, Neuroradiology, Universidade Federal de São Paulo, São Paolo, Brazil. (APJ)
Departments of Psychiatry, Neuroscience, and Radiology, Mount Sinai School of Medicine, New York, NY, US. (CYT, GP, DC)
Psychiatry, New York State Psychiatric Institute, New York, NY, US. (TDP)
Mental Health Care Line, Michael E. Debakey VA Medical Center, Houston, TX, US. (SJM)
Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, US. (SJM)
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, US. (JM)
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, US. (CGA)
Clinical Neuroscience Division, National Center for PTSD, West Haven, CT, US. (CGA, JK)
Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, US. (AJD)
Departmets of Psychiatry and Pathology and Cell Biology, College of Physicians and Surgeons of Columbia University, New York, NY, US. (AJD)
Comprehensive NeuroScience Corporation, Westchester, NY, US. (JMG)
Department of Psychiatry and Behavioral Sciences, University of Miami Health Sytems, Miami, FL, US. (CBN)
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Emory, GA, US. (MJO)
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, US. (AK, JK)
ID# 883
Tags: Amygdala, Early Life Stress, MRI, Non-Human Primates, Serotonin Transporter Gene, Stress