AnalyzeDirect Sieck GC, Van Balkom RHH, Prakash YS, Zhan WZ, Dekhuijzen PNR. Corticosteroid effects on diaphragm neuromuscular junctions. J Appl Physiol (1985). January 1999;86(1):114-122.
Full Text – Open Access
Publication Date
January 1999
How Analyze was Used
“A comprehensive image-analysis software package (ANALYZE …) running on a Sun 4/330 UNIX workstation was used to create three-dimensional (3-D) reconstructions of the digitized images and to make 2-D and 3-D morphometric measurements.”
Keywords
Adrenal Cortex Hormones/pharmacology
Animals
Diaphragm/drug effects/innervation
Glucocorticoids/pharmacology
Image Processing, Computer-Assisted
Immunohistochemistry
Male
Microscopy, Confocal
Motor Endplate/drug effects/ultrastructure
Motor Neurons/drug effects
Muscle Fibers, Skeletal/drug effects/ultrastructure
Neuromuscular Junction/drug effects/ultrastructure
Prednisolone/pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Presynaptic/drug effects/ultrastructure
Synaptic Transmission/drug effects
Thyroid Hormones/blood
Author Affiliation(s)
Department of Anesthesiology, Mayo Clinic and Foundation, Rochester, MN 55905, US. (GCS, YSP, WZZ)
Department of Physiology and Biophysics, Mayo Clinic and Foundation, Rochester, MN 55905, US. (GCS)
Department of Pulmonary Diseases, University Hospital Nijmegen, Nijmegen 6500 HB, The Netherlands (RHHVB, PNRD)
ID# 2889
Tags: Adrenal Cortex Hormones/pharmacology, Animals, Computer-Assisted Image Processing, Confocal Microscopy, Diaphragm/drug effects/innervation, Glucocorticoids/pharmacology, Immunohistochemistry, Male, Motor Endplate/drug effects/ultrastructure, Motor Neurons/drug effects, Neuromuscular Junction/drug effects/ultrastructure, Prednisolone/pharmacology, Presynaptic Receptors/drug effects/ultrastructure, Rats, Skeletal Muscle Fibers/drug effects/ultrastructure, Sprague-Dawley Rats, Synaptic Transmission/drug effects, Thyroid Hormones/blood